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Color code for Phase Status
Trial Phase Status
0
Trial Phase NOT STARTED
1
Trial Phase IN PROGRESS and RECRUITING PATIENTS
2
Trial Phase IN PROGRESS (Recruiting Completed)
3
Trial Phase COMPLETED
4
Trial SUSPENDED, TERMINATED or NOT INITIATED
In the chart below, click on the name of a Treatment or a Sponsor for DETAILED INFORMATION.
Click on a colored box for DETAILED INFORMATION about that trial phase.
Treatment Score Card
Click any column heading to sort the list.
TreatmentTreatment ClassPhase1Phase2Phase3Phase4Sort by this columnNDA StatusSponsor Name
AAV-hAADC-2 (was AV-201)Gene Therapy
3
0
0
0
Not Yet FiledGenzyme Corporation (GENZ)
ACP-103 (renamed pimavanserin)5ht2a/C Receptor Inverse Agonist
3
2
0
0
Not Yet FiledAcadia Pharmaceuticals, Inc.
ACR343Dopamine Agonist
3
0
0
0
Not ApplicableNeuroSearch
ADX48621Allosteric modulators
3
0
0
0
Not Yet FiledAddex Pharmaceuticals
AEOL 11207Antioxidant
0
0
0
0
Not Yet FiledAeolus Pharmaceuticals, Inc.
AL-108NAP peptide
0
0
0
0
Not Yet FiledAllon Therapeutics Inc.
AT2101.
0
0
0
0
Not Yet FiledAmicus Therapeutics
AV-133 (PET imaging compound)Imaging Agent (Diagnostic)
1
0
0
0
Not Yet FiledAvid RadioPharmaceuticals Inc.
Altropane (diagnostic radioimaging agent)Imaging Agent (Diagnostic)
3
3
1
0
Not Yet FiledAlseres Pharmaceuticals (was Boston Life Sciences)
Altropane (diagnostic radioimaging agent)(follow-up study)Imaging Agent (Diagnostic)
0
3
0
0
Not Yet FiledMolecular NeuroImaging
Angiotensin II BlockadeAce Inhibitor
1
0
0
0
Not Yet FiledGenoMed Inc. (GMED)
AplindoreDopamine Agonist
3
3
0
0
Not Yet FiledNeurogen Corporation
BIIB014 (was V2006)Adenosine Receptor Antagonist
3
4
0
0
Not Yet FiledBiogen Idec Inc.
CERE-120 (neurturin)Gene Therapy
3
3
0
0
Not Yet FiledCeregene, Inc.
CHF1512 (renamed V1512)Levodopa
3
3
0
0
Not Yet FiledGB Therapeutics
CoQ10 (Coenzyme Q10)Antioxidant
3
3
1
0
Not Yet FiledNational Institute of Neurological Disorders & Stroke
Cogane (PYM50028)Neuroprotective Factor
3
0
0
0
Not Yet FiledPhytopharm plc
DM-1992Levodopa
3
0
0
0
Not Yet FiledDepomed
DuodopaLevodopa
3
3
1
0
Not Yet FiledAbbott Laboratories
DynaCirc ® (isradipine)Calcium channel blocker
3
1
0
0
Approved for other conditionsNorthwestern University
E2007 (perampanel)AMPA receptor antagonist
3
3
4
0
Not Yet FiledEisai Medical Research, Inc.
Estrogen Replacement TherapyEstrogen Therapy
3
3
0
0
Approved for other conditionsParkinson Study Group
FP0011Glutamate blocker
3
3
0
0
Not Yet FiledFaust Pharmaceuticals
Fipamezole (JP-1730)Adrenergic Receptor Antagonist
3
3
0
0
Not Yet FiledBiovail Corp.
GDNF ( Glial derived neurotrophic factor ) - pump infusion deliveryNeurotrophic Factor
3
4
0
0
Not Yet FiledAmgen, Inc.
GDNF (Glial derived neurotrophic factor) gene therapyGene Therapy
0
0
0
0
Not Yet FiledNational Institute of Neurological Disorders and Stroke
GM1 GangliosideNeuroprotective Factor
3
1
0
0
Not Yet FiledFidia SpA
GPI 1485Neuroimmunophilin Ligand
3
3
4
0
Not Yet FiledSymphony Neuro Development Company
GPI 1485 (NET-PD)Neuroimmunophilin Ligand
3
3
0
0
Not Yet FiledNational Institute of Neurological Disorders and Stroke
Glutamic Acid Decarboxylase (GAD) Gene TherapyGene Therapy
3
3
0
0
Not Yet FiledNeurologix, Inc. (USA)
HP-200 (Zandopa)Ayurvedic
3
3
0
0
Not Yet FiledZandu Pharmaceutical Works Ltd
Hedgehog Pathway AgonistSmall Molecule Hedgehog Pathway Agonist
0
0
0
0
Not Yet FiledCuris, Inc.
IPX066Levodopa
3
3
1
0
FiledIMPAX Laboratories Inc.
Istradefylline (KW- 6002)Adenosine Receptor Antagonist
3
3
2
0
FDA Non-Approvable Letter ReceivedKyowa Pharmaceutical, Inc. - A U.S. Subsidiary of Kyowa Hakko Kogyo Co., LTD, Japan
LisurideDopamine Agonist
3
2
0
0
Not Yet FiledPrestwick Pharmaceuticals, Inc.
Lu02-750Dopamine Agonist
1
0
0
0
 .H. Lundbeck A/S
MX4565Estrogen Therapy
0
0
0
0
Not Yet FiledMigenix
Magnetic StimulationMagnetic Brain Stimulation
3
0
0
0
Not Yet FiledNational Center for Complementary and Alternative Medicine (NCCAM)
MinocyclineAntibiotic
3
3
0
0
Approved for other conditionsNational Institute of Neurological Disorders and Stroke
MitoQ (mitoquinone)Antioxidant
3
3
0
0
Not Yet FiledAntipodean Pharmaceuticals
Mucuna pruriensMedicinal Plant
2
0
0
0
Not Yet FiledNational Hospital for Neurology and Neurosurgery, London, UK.
ND0601; Transdermal Delivery Systems for the Treatment of Neurological DiseasesLevodopa
3
0
0
0
Not Yet FiledNeuroDerm Ltd. (Private Company. Operates as part of Ofakim Hi-Tech Ventures Ltd.)
NS2330Monoamine Uptake Inhibitor
3
3
4
0
Not ApplicableNeuroSearch
Neupro® (Rotigotine transdermal system)Dopamine Agonist
3
3
1
0
ApprovedUCB S.A.
Northera (was Droxidopa)norepinephrine agonist
3
3
2
0
Not Yet FiledChelsea Therapeutics
NurOwn bone marrow derived stem cellsStem Cells (Adult)
0
0
0
0
Not Yet FiledBrainStorm Cell Therapeutics
NuroPro (Diagnostic blood test).
3
0
0
0
Not Yet FiledPower3 Medical Products, Inc.
PD-02 (creatine)Antioxidant
3
3
1
0
Not Yet FiledNational Institute of Neurological Disorders & Stroke
PD01 (vaccine).
0
0
0
0
Not ApplicableAffiris AG
PN277Oligopeptide
0
0
0
0
Not Yet FiledProneuron Biotechnologies
Pardoprunox (SLV308)Dopamine Agonist
3
3
3
0
Not Yet FiledSolvay Pharmaceuticals, Inc. Subsidiary of Solvay SA
Paxil CR® (paroxetine CR) (SAD-PD)Anti Depressant
3
3
1
0
Approved for other conditionsNational Institute of Neurological Disorders & Stroke
PiclozotanSerotonin Receptor Agonist
3
3
0
0
Not Yet FiledAsubio Pharmaceuticals, Inc.
Pimavanserin (was ACP-103)5ht2a/C Receptor Inverse Agonist
3
3
2
0
Not Yet FiledAcadia Pharmaceuticals, Inc.
Preladenant (SCH 420814)Adenosine Receptor Antagonist
3
1
0
0
Not Yet FiledSchering-Plough
ProSavin Gene TherapyGene Therapy
1
1
0
0
Not Yet FiledOxford BioMedica
Requip XL 24-Hour (Ropinirole HC1)Dopamine Agonist
3
3
3
0
ApprovedGlaxoSmithKline
Rna Interference (RNAi)Gene Therapy
0
0
0
0
Not Yet FiledAlnylam Pharmaceuticals Inc.
SNN0031Neuroprotective protein
2
2
0
0
Not Yet FiledNeuroNova
SR57667BNeuroprotective Factor
3
3
0
0
Not Yet FiledSanofi-Aventis
SYN-115Adenosine Receptor Antagonist
3
3
0
0
Not Yet FiledSynosia Therapeutics
Sarizotan (EMD 128130)Dopamine Agonist
3
3
4
0
Not Yet FiledMerck KGaA
SpheramineRetinal Pigmented Epithelial (RPE) Cells
3
4
0
0
Not Yet FiledBayer Schering Pharma AG
T9001Gene Therapy
0
0
0
0
Not ApplicableQRxPharma
TalampanelGlutamate blocker
3
3
0
0
Not Yet FiledNational Institute of Neurological Disorders and Stroke
V1512 (was CH1512)Levodopa
3
3
0
0
Not Yet FiledVernalis plc
V2006 (renamed BIIB014)Adenosine Receptor Antagonist
3
0
0
0
Not Yet FiledVernalis plc
VP025Anti Inflammatory Agent
3
0
0
0
Not Yet FiledVasogen, Inc.
VPS41Neuroprotective protein
0
0
0
0
Not Yet FiledUniversity of Alabama
VR040Dopamine Agonist
3
3
0
0
Not Yet FiledVectura Group plc
Vaccine.
0
0
0
0
Not ApplicableU of Nebraska Medical Center, Center for Neurovirology and Neurodegenerative Disorders
Vadova (IPX054)Levodopa
3
3
4
0
FDA Non-Approvable Letter ReceivedIMPAX Laboratories Inc.
ValerianMedicinal Plant
3
3
0
0
Not Yet FiledNational Center for Complementary and Alternative Medicine (NCCAM)
Venlafaxine (SAD PD)Anti Depressant
3
3
1
0
Not Yet FiledNational Institute of Neurological Disorders and Stroke
XP21279 Levodopa
3
1
0
0
Not Yet FiledXenoPort, Inc.
ZonisamideAnti Epileptic
3
3
3
0
Approved for other conditionsDainippon Sumitomo Pharma Co.,Ltd.
AV-201 - see AAV-hAADC-2.
0
0
0
0
 .Avigen, Inc.
Aripiprazole - see Abilify®.
0
0
0
0
 .Bristol Myers Squibb
Azilect® (rasagiline mesylate) ADAGIO StudyMonoamine Oxidase Inhibitor
0
0
3
0
Not Yet FiledTeva Pharmaceutical Industries Ltd.
CERE-120 (neurturin)(protocol 2)Gene Therapy
1
0
0
0
 .Ceregene, Inc.
Creatine - See PD-02.
0
0
0
0
 .National Institute of Neurological Disorders and Stroke
Droxidopa - see Northera.
0
0
0
0
 .Chelsea Therapeutics
GDNF (Glial derived neurotrophic factor) - Encapsulated cell deliveryNeurotrophic Factor
0
0
0
0
Not Yet FiledLund University
GDNF (Glial derived neurotrophic factor) - convection enhanced deliveryNeurotrophic Factor
0
0
0
0
Not Yet FiledMedGenesis Therapeutix Inc.
GDNF (Glial derived neurotrophic factor) - intravenous deliveryNeurotrophic Factor
0
0
0
0
Not Yet FiledUniversity of California. Los Angeles
GDNF (Glial derived neurotrophic factor) - stem cell deliveryNeurotrophic Factor
0
0
0
0
Not Yet FiledUniversity of Wisconsin
Isradipine - See DynaCirc®.
0
0
0
0
 .Northwestern University
JP1730 - see Fipamezole.
0
0
0
0
 .Biovail Corporation
KW-6002 see Istradefylline.
0
0
0
0
 .Kyowa Pharmaceutical, Inc. - A U.S. Subsidiary of Kyowa Hakko Kogyo Co., LTD, Japan
Lu AA47070Adenosine Receptor Antagonist
2
0
0
0
Not ApplicableH. Lundbeck A/S
Memantine hydrochloride - see Namenda® .
0
0
0
0
 .Forest Pharmaceuticals A Subsidiary of Forest Labs
ProNeura (sustained drug delivery system).
0
0
0
0
Not ApplicableTitan Pharmaceuticals, Inc.
Rasagiline mesylate - see Azilect®.
0
0
0
0
 .Teva Pharmaceutical Industries Ltd.
RifampicinAntibiotic
0
0
0
0
Approved for other conditionsUniversity of California, Santa Cruz
Ropinirole HC1 - see REQUIP XL 24-Hour.
0
0
0
0
 .GlaxoSmithKline
Rotigotine transdermal system - see Neupro®.
0
0
0
0
ApprovedSchwarz Pharma AG
SLV-308 (see Pardoprunox)Dopamine Agonist
0
0
0
0
 .Solvay Pharmaceuticals, Inc. Subsidiary of Solvay SA
SafinamideMonoamine Oxidase Inhibitor
3
3
3
0
Not Yet FiledMerck Serono S.A
Selegiline hydrochloride - see Zelapar®.
0
0
0
0
ApprovedValeant Pharmaceuticals International
BOTOX® (botulinum toxin type A).
0
0
0
1
Approved for other conditionsUniversity of Cincinnati
Zelapar® (selegiline hydrochloride) orally disintegrating tabletsMonoamine Oxidase Inhibitor
3
3
3
1
ApprovedValeant Pharmaceuticals International
CEP-1347Kinases Inhibitor
3
4
4
2
Not Yet FiledCephalon inc.
Keppra® (levetiracetam)Anti Convulsant
3
3
0
2
Approved for other conditionsUCB S.A.
Namenda® (memantine hydrochloride) NMDA receptor antagonist
3
3
3
2
Approved for other conditionsForest Pharmaceuticals A Subsidiary of Forest Labs
Abilify® (aripiprazole)Anti Psychotic
3
3
3
3
Approved for other conditionsBristol Myers Squibb
Azilect® (rasagiline mesylate)Monoamine Oxidase Inhibitor
3
3
3
3
ApprovedTeva Pharmaceutical Industries Ltd.
Ritalin® (Methylphenidate)norepinephrine agonist
0
3
0
3
Approved for other conditionsUniversity of Cincinnati

 
 
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